UN warns of bird flu resurgence, new Asian strain
AP Associated Press updated 8/29/2011 ROME — The United Nations warned Monday of a possible resurgence of the deadly bird flu virus, saying wild bird migrations had brought it back to previously virus-free countries and that a mutant strain was spreading in Asia. A mutant strain of H5N1, which can apparently sidestep defenses of existing vaccines, is spreading in China and Vietnam, Tthe U.N. Food and Agriculture Organization said in a statement Monday. It urged greater surveillance to ensure that any outbreaks are contained………………
…………………The virus was eliminated from most of the 63 countries infected at its peak in 2006, but it remained endemic in six countries: Bangladesh, China, Egypt, India, Indonesia and Vietnam.
The number of outbreaks in poultry and wild bird populations shrank from a high of 4000 to 302 in mid-2008, but outbreaks have risen progressively since, with almost 800 cases reported in 2010-2011, FAO said.
“The general departure from the progressive decline in 2004-2008 could mean that there will be a flare-up of H5N1 this fall and winter, with people unexpectedly finding the virus in their backyard,” Lubroth said in a statement.
It’s almost flu season. Here we go again. Already the folks at my husband’s work place are planning to “get those flu shots“ because their doctors and health care professionals are stressing the need. Once again we will duck our heads and avoid them (the shots that is). But flu is real and we will step up the preventatives and that includes Vitamin D and taking silver solutions. Our knowledge of what can be in the shots is enough to make us abhor the in your face push to get everyone vaccinated with the cocktail of who knows which strains some of which originated in the research laboratories of our compartmentalized medical geniuses.
But some of the flu strains circulating in the wild have mutated (as they always do continuously) beyond the cocktail’s effects.
And some strains very likely will have been affected by the Fukushima radiation plumes that have blanketed the Northern Hemisphere since March 11, 2011, this article dated March 17, 2011, shows that flu watchers have been preparing since the nuclear event for the eventuality ; http://mater-readstoomuch.blogspot.com/2011/03/connecting-tragedy-dominos-fukushima.html
OIE reports on confirmed H5N1 in wild birds identified throughout Japan, including northern Japan. Sequences from three isolates from these outbreaks have been made public at Genbank. Two of the three (in Hokkaido and Fukushima) have S227R. All three sequences are the Fujian strain (clade 2.3.2) which have been circulating in wild birds for several years, including the large outbreaks in Japan, South Korea, and Russia in the spring of 2008. The clade 2.3.2 sequences have two additional receptor binding domain changes (V223I and M230I), which were present in the clade 2.2 sequences from the Gharbiya cluster in Egypt in late 2006. The Gharbiya cluster is the largest H5N1 cluster in Egypt reported to date. All three patients died and the RBD changes raised concerns of increase transmission in human.
The recent acquisition of S227R increased concerns because of the known changes in receptor binding specificity due to S227N, which was predicted and confirmed in 2 of the 4 sequences from Turkey in 2006. The recent reports of two confirmed cases in Kamalpur, a Bangladesh slum have increased concerns that clade 2.3.2 has migrated to Bangladesh and is involved in the two recent cases (as well as symptomatic contacts). Read the rest; http://www.recombinomics.com/News/03171102/H5N1_Fukushima_Radiation_WB.html
I include this next article to beg the question, “Does this give you confidence to roll up your sleeve or hold your baby down to take a flu shot, after reading about some of the variables that go into the choice of the flu cocktail we have been urged most stridently to submit our and our children’s immune systems to?
August 8, 2011; http://www.recombinomics.com/News/08081101/H1N1_Japan_LR_More.html
More H1N1 Low Reactors In Japan Raises Vaccine Concerns
This weekend the NIID in Japan released a series of H1N1 sequences, including 40 HA sequences from 2011. Like earlier releases, these sequences had a large number of changes at positions 156-159 which are associated with LOW REACTOR results when tested against the current H1N1 vaccine directed against California/7/2009. The latest series had 14 changes at positions 156-159 with a distribution of 5, 5, 3, 1. The earlier sets of sequences where dominated by changes at position 158 (6, 1, 9, 2 and 1, 3, 5, 1). This changing profile indicates these low reactor changes are present in the clinical sample and not due to random mutations selected by the cell line used to isolate H1N1 virus, as suggested by the CDC in the FDA’s vaccine advisory committee meeting. The committee discounted the low reactor changes reported by other WHO regional centers, such as Mill Hill in England and voted unanimously to leave all three vaccine targets unchanged, for the 2011/2012 flu season in the northern hemisphere. This vaccine, which is identical to vaccine for the 2010/2011 season, will soon be shipping throughout the northern hemisphere, raising concerns that the vaccination program will fail.
This concern was increased by recently released sequences (by the CDC at GISAID), which included a construct of a new H1N1 target using H1 and N1 on a PR8 genetic background, as well as three new H3N2 targets and three new influenza B targets, indicating the CDC now has major reservations of use of 2009 targets. The new constructs largely use 2010 isolates, like A/South Carolina/02/2010 for the H1N1 target.. The H1N1 target also has K157E and Q226R acknowledging a need for changes in these two critical regions. Two way testing of the new H1N1 target was listed as LOW / FAIL indicating the old vaccine poorly recognized the new target, and a vaccine against the new target poorly recognized the old target (Califorenia/7).
The latest data from Japan once again highlights the reliance of the CDC and WHO on the paradigm of random mutations to be hazardous to the world’s health. The recommendations to WHO and the FDA in the United States was largely based on the assumption that the frequent detection of changes at positions 156-159 was due to lab selection of random mutations, as well as similar changes at positions 225 (D225G and D225N) and 226 (Q226R). the testing of new H1N1 targets with changes at positions 157 and 226 acknowledges that the “lab errors” due to “spontaneous mutations” was false. However in the southern portion of the United States the new school year begins this week and more school seasons will begin later this month in areas to the north.
Last season pneumonia and influenza death rates were at record levels, and the recent results from Japan raises concerns that changes at positions 156-159 will lead to immunological escape, and changes at positions 225 and 226 will target the lungs, leading to more severe H1N1 cases.
ME? I’m more comfortable taking sun baths when I can, dosing on Cod Liver Oil and Silver Solutions, Black Strap Molasses, and such like, eating well, exercising, and praying for protection from flu. I dread the day when or if force is increased upon us to take the shots, bottom line, I just don’t trust them.
To keep up with the studies this is a place to go; http://www.recombinomics.com/whats_new.htm
Stay safe and healthy and informed.